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Dr. Slim Chiha

Lab 310
Tel +49 221 470 4269


[1] Synthesis of B-Ring-Modified Steroids through BF3-Promoted Rearrangement/Substitution of 6 beta-Hydroxy-5,19-cyclosteroids, D. P. Kranz, S. Chiha, A. M. Z. Greffen, J. M. Neudorfl, H. G. Schmalz, Org. Lett., 201214 (14), 3692. 10.1021/ol301532w

[2] Design and Stereoselective Synthesis of ProM-2: A Spirocyclic Diproline Mimetic with Polyproline Type II (PPII) Helix Conformation, C. Reuter, R. Opitz, A. Soicke, S. Dohmen, M. Barone, S. Chiha, M. T. Klein, J. M. Neudorfl, R. Kuhne, H. G. Schmalz, Chem. Eur. J., 201521 (23), 8464, 10.1002/chem.201406493

[3] Design and Synthesis of Building Blocks for PPII-Helix Secondary-Structure Mimetics: A Stereoselective Entry to 4-Substituted 5-Vinylprolines, S. Chiha, A. Soicke, M. Barone, M. Muller, J. Bruns, R. Opitz, J. M. Neudorfl, R. Kuhne, H. G. Schmalz, Eur. J. Org. Chem., 20182018 (4), 455, 10.1002/ejoc.201701584

[4] A Stereoselective Synthesis of the ACE Inhibitor Trandolapril, S. Chiha, M. Spilles, J. M. Neudorfl, H. G. Schmalz, Synlett, 201930 (7), 813, 10.1055/s-0037-1612306

[5] Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells, M. Barone, M. Müller, S. Chiha, J. Ren, D. Albat, A. Soicke, S. Dohmen, M. Klein, J. Bruns, M. van Dinther, R. Opitz, P. Lindemann, M. Beerbaum, K. Motzny, Y. Roske, P. Schmieder, R. Volkmer, M. Nazaré, U. Heinemann, H. Oschkinat, P. ten Dijke, H.-G-Schmalz, R. Kühne, PNAS 2020117 (47), 29684, 10.1073/pnas.2007213117